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Several clinical trials have confirmed the efficacy and safety of nusinersen, leading to better motor milestone responses and higher event-free survival rates

Clin Pharmacol Ther 1991;50:695-701

For patients who want a deeper dive into how biomarkers fit into this picture, the institute's resource on longevity biomarkers helps connect hormone health to a broader longevity framework

Future large-scale, well-designed clinical trials will be essential to confirm their therapeutic potential, clarify the contribution of metabolic versus immunological effects, and define their role within the treatment algorithm of PsO and PsA

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